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KMID : 0360120070290060548
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Journal of the Korean Society of Maxillofacial Plastic Reconstructive Surgeons
2007 Volume.29 No. 6 p.548 ~ p.553
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A Case report of Kikuchi-Fujimoto Disease
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Jang Tae-Hwa
Lee Sang-Han
Kwon Tae-Geon
Jang Hyun-Jung
Kim Chin-Soo
Kim Jin-Wook
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Abstract
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Kikuchi-Fujimoto disease is a rare disease first described in 1972 by Kikuchi and Fujimoto et al. The disease is described as a benign and unusual self-limiting histiocytic necrotizing lymphadenitis of unknown origin, which is characterized histologically by necrotic foci surrounded by histiocytic aggregates, is usually manifested with lymphadenopathy and high fever. This disease mostly affects young Asian women between 20 and 30 years of age and has rarely been reported in children. Main symptoms are indolent or light tender, enlarged lymph nodes in the neck area. The correct diagnosis requires the histologic examination of the lymph node. Kikuchi-Fujimoto disease is easily confused histologically and clinically with lymphoma and systemic lupus erythematosis histologically and clinically. Although it is an uncommon cause of fever of unknown origin, early recognition of KFD is very important and will minimize potentially harmful and unnecessary evaluations and treatments. We reported a case, a 23-year old man who had Kikuchi-Fujimoto disease with a literature review.
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KEYWORD
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Kikuchi, Fujimoto, Necrotizing Lymphadenitis, Karyorrhexis, Fever
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